Fertility

Adenomyosis vs endometriosis – what’s the difference, and how do we navigate fertility treatment?

24 Mar 2025


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When it comes to adenomyosis vs endometriosis, the two are often confused

However, they’re different conditions. In either case, the questions we so often get asked here on team TRB are how do they impact fertility, and what can you do if you have one (or both)?

We sat down with Dr. Shannon Alexa at Main Line Fertility, an OB/GYN specialized in Reproductive Endocrinology, to break it all down.

This episode is powered by The Prelude Network, the largest and fastest-growing network of fertility clinics in the U.S. and Canada, offering cutting-edge treatment and personalized care.

We’ll cover:

  • The key biological differences between adenomyosis and endometriosis

  • How each condition affects fertility and implantation

  • Why diagnosis can be so difficult—and how to advocate for clarity

  • Treatment options, from medication to surgery

  • How adenomyosis and endometriosis impact IVF success rates

  • Ways to optimize the uterus for implantation

  • What to know about pregnancy risks and monitoring

Listen now

Listen in full above or via your favourite Podcast app.

Simply click ‘play’ on the embedded player or listen via any of the following apps:

Apple | Spotify | Google

Want to learn more or speak with a fertility specialist? Visit The Prelude Network to find your nearest clinic and request an appointment.

Up next: IVF success rates for specific situations (from PCOS to endometriosis, over 40 & more, we break it down)

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