Some have read that PGT can be controversial, with some clinics saying that PGD-A can be inaccurate and give false positives for abnormality, leading to perfectly good embryos being discarded; also, that a day 5 blastocyst which shows abnormal chromosomes can self-correct and produce a perfectly healthy baby.
What do you Feel about this Stance and what in your View are the Pros and Cons?
Of course, all medical tests are not 100 % certain. But, when there is a high risk of creating abnormal embryos that could lead to miscarriages or babies with syndromes, or even implantation failures, it is recommended to discuss individually with each couple or woman before starting the treatment, and to explain the pros and cons of this test.
Please can you Define the Term ‘Mosaic Embryo’? Do you think they Should be Transferred or Discarded?
The mosaic embryo is an embryo that has both normal and abnormal cells (some of its cells are absolutely normal in terms of chromosomes, whereas others are abnormal). The recommendation to transfer or not depends on different aspects: the number of chromosomes involving the mosaicism-for instance sexual chromosomes, 21, 13 and 18 should be excluded, the number of chromosomes involved in the abnormality (one or more chromosomes), etc.
Can Testing Harm the Embryo?
Naturally, it is an invasive test that could eventually harm the embryo. That is the reason why it is extremely necessary to do it in a very good clinic with a high-tech laboratory and senior biologists.
Do People use this Method to Find Out the Sex of their Embryo?
It could be the case in some countries, but it is not possible in Spain.
How much does PGT Cost?
It depends on the type of genetic testing. For instance, in PGT-A, it depends on the number of embryos biopsied. Our team of Patient Care coordinators will be more than happy to answer this type of question if you send an e-mail to email@example.com
For Someone who has Few Embryos, a low AMH and is over 40, would you recommend PGT?
Women with a low ovarian reserve, or with only one embryo are the ones that benefit less from this technique. On the other hand, if a woman is older than 40, there is a high risk of abnormality and then it is necessary to discuss with them if they want to carry on with the test or not.
Thanks to Clinica Tambre for answering our readers’ questions. Watch back their #fertilityexpertslive all about PGT here. Make sure to tune in on Instagram to hear more on the topic!
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