DHEA vs DHA for fertility – what’s the important difference?
What should we know about DHA vs DHEA for fertility?
These two substances might already be on your radar if you’re currently TTC (trying to conceive). And although their names look similar, they are actually very different, and play very separate roles in your body – especially when it comes to addressing fertility concerns.
Understanding the important difference between DHA and DHEA can help you make more informed decisions on your TTC journey.
So, we’ve put together this mini-guide to bust some of the jargon and compare the two, along with team-approved tips for getting started with supplementation.
Let’s get into it.
Is DHA similar to DHEA?
The short answer is no – DHA and DHEA are similar in name only, and that’s about it.
DHA is an omega-3 fatty acid that is a component of almost every cell in the body, and is crucial for overall health as well as reproductive health. It is commonly included in prenatal supplements, but it does not directly influence your hormone levels.
On the other hand, DHEA is a hormone that directly affects the reproductive system by contributing to hormone production. Because of this, it is a more controlled substance, and whilst it’s available in over-the-counter supplements in the USA, it is only available on a doctor’s prescription in the UK and the rest of Europe right now.
So, whilst DHA and DHEA are both associated with fertility support, their roles in the body are more or less completely separate.
Here’s a little more detail on the hows and the whys.

What is DHEA?
Briefly, DHEA, or dehydroepiandrosterone, is a steroid hormone produced naturally from cholesterol by your adrenal glands, and, in smaller amounts, by your ovaries and brain.
It’s often referred to as a “precursor” hormone because it helps produce other important hormones, such as estrogen and testosterone.
As we age, our DHEA levels do naturally decline which can impact fertility. Low levels of DHEA have been associated with poor ovarian reserve in particular – read back to TRB founder Eloise’s IVF prep journey for more on the basics and optimal levels for treatment.
In recent years, DHEA supplementation has gained attention for its potential to improve ovarian function, both in women with diminished ovarian reserve (have a look at this study for more on this) and also in women having fertility treatment.
What is DHA?
DHA, or docosahexaenoic acid, is an omega-3 fatty acid, commonly found in fish oils and algae. DHA is essential for so many of our bodily functions, particularly for brain and eye health.
During early pregnancy, DHA is critical for the development of the baby’s brain and retina, which is why it’s often included in prenatal vitamins.
However, DHA isn’t just important during pregnancy – it’s also crucial before conception. Omega-3 fatty acids, including DHA, help reduce inflammation and protect DNA from oxidative damage, and studies have also shown that an increased intake may improve sperm health and quality.

Should I take DHEA or DHA for fertility?
Deciding whether to take DHEA or DHA for fertility depends on your specific needs and circumstances, and it is super important to talk to your fertility team to decide which is best for you.
Usually, it’s not necessarily a matter of choosing one over the other – rather, it’s about understanding which can support your unique fertility profile.
DHEA fertility support options
Diet support: Whilst there are no food sources of DHEA, healthy fat and protein sources can help create cholesterol, which could, in turn, boost DHEA production. You could try avocado, nuts and seeds, as well as wild-caught fish, chicken, and eggs.
Supplement support: Supplementation might be recommended if you’re facing specific fertility challenges, especially when preparing for IVF. DHEA supplementation should only really be done under the guidance of a healthcare provider though, as oversupplementation can lead to hormonal imbalance.
Team TRB tip: We’d recommend asking your doctor about the groundbreaking Fertinatal® supplement by Ovaterra. Eloises go-to in the lead-up to her fifth and final IVF cycle, the formulation has been specifically for women aged over 35, to support ovarian health.
You can skip straight to Ovaterra to learn more, and get 15% off the entire range – including the Fertinatal® DHEA – with code TRB15.
How to take DHA for fertility
Dietary support: Salmon, mackerel and sardines – basically any really good-quality oily fish – are the top-notch food source of DHA, and you can get a plant-based boost from nuts and seeds like chia and walnut.
Supplement support: Next to a well thought-out approach to diet, DHA might be a good addition to your supplement routine if you are looking to support your overall reproductive health. DHA is generally considered safe and is widely recommended for those trying to conceive.
Team TRB tip: Taken by our founder Eloise during preconception and pregnancy, the legendary Zita West Vital DHA packs in a rich boost of omega-3s and is designed to protect both partners’ DNA from oxidative damage during preconception, as well as to support normal fertility and healthy sperm production in male partners.
Grab 10% off the entire Zita West supplement range (US and UK), with code TRB10* at checkout.
DHEA vs DHA for fertility – the bottom line
Both DHA and DHEA are important for fertility, but they serve very different purposes.
DHA is an omega-3 fatty acid that supports overall reproductive health by reducing inflammation and aiding in hormone regulation. DHEA, on the other hand, is a hormone that may improve ovarian function and egg quality, but usually needs a prescription if you’re outside of the US.
If you’re trying to conceive and looking to support yourself in the best way, book in for a chat with your healthcare provider before starting any new supplement – especially if you’re considering DHEA, as its use should be closely monitored to ensure optimal results.
*TRB10 is valid once per customer only. Excludes subscription purchase. This offer cannot be used in conjunction with any other offer. Zita West terms of the site apply.
